Biphasic calcium phosphate as a bone substitute
نویسندگان
چکیده
منابع مشابه
Evaluation of New Biphasic Calcium Phosphate Bone Substitute: Rabbit Femur Defect Model and Preliminary Clinical Results
Autogenous bone grafting, used to repair bone defects, is limited and the donor site can experience complications. Compared to autogenous bone graft, artificial bones have different porosity, which might make them suitable alternatives to bone grafts. Here, two porous biphasic calcium phosphate bone substitutes, namely Bicera™ and Triosite™, are used in an animal study and clinical practice to ...
متن کاملScaffold Effects of Microporous Biphasic Calcium Phosphate Granules and Role of HPMC Hydrogels in Injectable Multiphasic Bone Substitute Developments
Calcium phosphate granules associated with hydrogels were developed as bone substitutes for various clinical applications. These Injectable Bone Substitutes (IBS) should regenerate bone tissue. The efficiency of these multiphasic materials was due to the osteogenic properties of the Microporous Biphasic Calcium phosphate (BCP) granules. The hydrosoluble polymers associated to BCP were considere...
متن کاملImprovement of osteogenic potential of biphasic calcium phosphate bone substitute coated with synthetic cell binding peptide sequences
PURPOSE The aim of this study was to evaluate the improvement of osteogenic potential of biphasic calcium phosphate (BCP) bone substitute coated with synthetic cell-binding peptide sequences in a standardized rabbit sinus model. METHODS Standardized 6-mm diameter defects were created bilaterally on the maxillary sinus of ten male New Zealand white rabbits, receiving BCP bone substitute coated...
متن کاملThe Effect of Covalently Immobilized FGF-2 on Biphasic Calcium Phosphate Bone Substitute on Enhanced Biological Compatibility and Activity
The purpose of this research was to covalently graft fibroblast growth factor 2 (FGF-2) onto biphasic calcium phosphate (BCP) via a bifunctional cross-linker technique and to estimate the optimal dose of FGF-2 resulting in the best osteogenic differentiation of human mesenchymal stem cells (hMSCs). SEM observation revealed that the surface of the 100 ng FGF-2 coated BCP was completely covered w...
متن کاملPolymer-calcium phosphate composites for use as an injectable bone substitute
Calcium phosphate (CP) materials have been used extensively for bone replacement and augmentation due to their similarity to the mineral component of bone. In addition to being non-toxic, they are biocompatible, not recognized as foreign in the body, and most importantly, exhibit bioactive behavior, being integrated into the tissue by the same processes active in remodeling healthy bone. This l...
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ژورنال
عنوان ژورنال: Frontiers in Bioengineering and Biotechnology
سال: 2016
ISSN: 2296-4185
DOI: 10.3389/conf.fbioe.2016.01.00487